Autor: Clinical genetics
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Large multiple sclerosis brain cohort reveals biological differences linked to disease severity
Why does multiple sclerosis progress quickly in some people, while others remain stable for years? Researchers from the Netherlands Institute for Neuroscience have identified biological patterns in the brain that may help explain these differences. The…
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Eating disorders and obsessive-compulsive disorder show shared brain gene expression changes
Researchers at the Icahn School of Medicine at Mount Sinai and the Lieber Institute for Brain Development have identified substantial similarities in brain gene activity among people with eating disorders and obsessive-compulsive disorder (OCD), provid…
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Eating disorders and obsessive-compulsive disorder show shared brain gene expression changes
Researchers at the Icahn School of Medicine at Mount Sinai and the Lieber Institute for Brain Development have identified substantial similarities in brain gene activity among people with eating disorders and obsessive-compulsive disorder (OCD), provid…
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Thirty years later: A reappraisal of Alzheimer’s disease risk in Japanese APOE-e4 homozygotes
Researchers at Niigata University have conducted the first comprehensive reappraisal in nearly 30 years of the risk of Alzheimer’s disease (AD) associated with APOE-e4 homozygosity (e4*4) in the Japanese population. Their findings, published in the jou…
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Thirty years later: A reappraisal of Alzheimer’s disease risk in Japanese APOE-e4 homozygotes
Researchers at Niigata University have conducted the first comprehensive reappraisal in nearly 30 years of the risk of Alzheimer’s disease (AD) associated with APOE-e4 homozygosity (e4*4) in the Japanese population. Their findings, published in the jou…
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Reproduction affects health—and so does biological sex
Starting one’s sex life and having children at a young age can run in the family. But can pregnancy have beneficial health effects, and do the partner’s genes contribute to them? «We are just beginning to understand how pregnancy affects health later i…
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Reproduction affects health—and so does biological sex
Starting one’s sex life and having children at a young age can run in the family. But can pregnancy have beneficial health effects, and do the partner’s genes contribute to them? «We are just beginning to understand how pregnancy affects health later i…
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New tool helps uncover rare genetic mutations in common diseases, including Parkinson’s
Studies of genetics conducted in yeast cells, human neurons, mice or other model systems often reveal networks of genes that could contribute to complex diseases, such as breast cancer, type 2 diabetes and Parkinson’s disease. But those findings don’t …
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New tool helps uncover rare genetic mutations in common diseases, including Parkinson’s
Studies of genetics conducted in yeast cells, human neurons, mice or other model systems often reveal networks of genes that could contribute to complex diseases, such as breast cancer, type 2 diabetes and Parkinson’s disease. But those findings don’t …
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First use of precision editing to study human embryo development reveals role of master gene
Research led by the University of Cambridge Loke Center for Trophoblast Research has shown that a genome-editing technique can be used to alter a single gene in human embryonic cells, enabling the study of very early human development in unparalleled d…