Categoría: Articulos
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What happens when brain tumors return? International study tracks genetic changes behind recurring cancers
When patients are diagnosed with certain brain tumors, one of the biggest unanswered questions is what happens when the cancer returns. Among those are IDH-mutant gliomas, a group of brain tumors that invariably recur despite advances in treatment.
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What happens when brain tumors return? International study tracks genetic changes behind recurring cancers
When patients are diagnosed with certain brain tumors, one of the biggest unanswered questions is what happens when the cancer returns. Among those are IDH-mutant gliomas, a group of brain tumors that invariably recur despite advances in treatment.
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Reversing age by reprogramming gene expression networks
Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified «hallmarks of aging» that not only present specific processes impacted by age, but are also thought of as levers that, if successfully ta…
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Reversing age by reprogramming gene expression networks
Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified «hallmarks of aging» that not only present specific processes impacted by age, but are also thought of as levers that, if successfully ta…
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Reversible genetic switches could give cancer immunotherapy more precise control
A genetic switch that activates immune cells as they fight tumors: this is the new strategy developed by an international research team coordinated by Velia Siciliano at the Istituto Italiano di Tecnologia (IIT—Italian Institute of Technology) in Naple…
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Reversible genetic switches could give cancer immunotherapy more precise control
A genetic switch that activates immune cells as they fight tumors: this is the new strategy developed by an international research team coordinated by Velia Siciliano at the Istituto Italiano di Tecnologia (IIT—Italian Institute of Technology) in Naple…
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Presubmission Pathologic Quality Control for FoundationOne CDx Comprehensive Genomic Profiling
Comprehensive genomic profiling using FoundationOne CDx (F1CDx) requires formalin-fixed, paraffin-embedded specimens with sufficient tumor area and DNA yield. Presubmission pathologic assessment is critical but has not been systematically evaluated in …
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A drug can make children with the most common form of dwarfism taller—but height isn’t the same as a better life
A drug that helps children with the most common form of dwarfism grow taller has sparked an ethical debate within the dwarfism community.
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A drug can make children with the most common form of dwarfism taller—but height isn’t the same as a better life
A drug that helps children with the most common form of dwarfism grow taller has sparked an ethical debate within the dwarfism community.
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Trapping cancer-driving DNA rings outside cell nucleus silences their genes, researchers find
Cells from rapidly growing, highly metastatic tumors often contain numerous rings of extrachromosomal DNA (ecDNA). This circular DNA frequently carries oncogenes—genes that promote cancer. Researchers have long sought vulnerabilities in these DNA rings…