Categoría: Noticias
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Updated cancer treatment framework offers new guidance on actionability and resistance biomarkers
ESMO has published version 2 of the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT), a major update to the internationally recognized precision oncology framework that helps oncologists assess the clinical relevance of molecular alte…
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Updated cancer treatment framework offers new guidance on actionability and resistance biomarkers
ESMO has published version 2 of the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT), a major update to the internationally recognized precision oncology framework that helps oncologists assess the clinical relevance of molecular alte…
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New gene-editing approach shows promise in treating Huntington’s disease in mice
Huntington’s disease is caused by repetitive «stutters» in DNA—specifically repeated CAG sequences—that expand abnormally over time, leading to toxic protein accumulation that contributes to the progression of the disease. There is currently no cure fo…
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New gene-editing approach shows promise in treating Huntington’s disease in mice
Huntington’s disease is caused by repetitive «stutters» in DNA—specifically repeated CAG sequences—that expand abnormally over time, leading to toxic protein accumulation that contributes to the progression of the disease. There is currently no cure fo…
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Liver tumors form without detectable driver mutations in mice, revealing epigenetic route
Cancers can develop through epigenetic pathways even without driver gene mutations (DGMs), according to a study from Science Tokyo. Researchers uncovered the YAP1–TEAD–TET1 axis, which triggers DNA demethylation and activates multiple oncogenes in hepa…
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Liver tumors form without detectable driver mutations in mice, revealing epigenetic route
Cancers can develop through epigenetic pathways even without driver gene mutations (DGMs), according to a study from Science Tokyo. Researchers uncovered the YAP1–TEAD–TET1 axis, which triggers DNA demethylation and activates multiple oncogenes in hepa…
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Comprehensive DNA sequencing reveals hidden drivers of cancer
Michigan’s Oncology Sequencing Program, or MiOncoSeq, was the first of its kind in the nation to sequence patient tumors. Launched in 2010, the program analyzes DNA and RNA from normal tissue and tumors to identify alterations that could help guide tre…
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Comprehensive DNA sequencing reveals hidden drivers of cancer
Michigan’s Oncology Sequencing Program, or MiOncoSeq, was the first of its kind in the nation to sequence patient tumors. Launched in 2010, the program analyzes DNA and RNA from normal tissue and tumors to identify alterations that could help guide tre…
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MRI scans and DNA data uncover new genetic links to fatty liver disease
Fatty liver disease is characterized by the accumulation of triglycerides—a type of fat—in the liver. The disease has a strong genetic component, but until now, knowledge about which genes influence its development has been limited. To gain a better un…
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MRI scans and DNA data uncover new genetic links to fatty liver disease
Fatty liver disease is characterized by the accumulation of triglycerides—a type of fat—in the liver. The disease has a strong genetic component, but until now, knowledge about which genes influence its development has been limited. To gain a better un…