Etiqueta: JMolDiagn

Bile duct brushings are noninvasive samplings of cells from the biliary tract for cytologic evaluation and are useful to diagnose pancreaticobiliary malignancies. Although specificity of cytology is satisfactory, sensitivity is inherently low because o…

The Editors gratefully acknowledge the generous assistance of the following reviewers who served The Journal of Molecular Diagnostics between January 1 and December 31, 2025.

High failure rates in targeted capture sequencing of solid tumors—especially from formalin-fixed, paraffin-embedded samples—limit the clinical application of next-generation sequencing. Current wet-laboratory quality control (QC) relies on rigid, prede…

The Idylla GeneFusion Assay (Biocartis) detects gene fusions with fusion-specific and expression imbalance methods. The purpose of this study was to evaluate the diagnostic utility of detecting fusions with expression imbalance alone in non-small cell …

The Idylla GeneFusion Assay detects gene fusions with fusion-specific and expression imbalance methods. The purpose of this study was to evaluate the diagnostic utility of detecting fusions with expression imbalance alone in non–small-cell lung cancer….

Previous work has shown that circulating miR-371a-3p has higher sensitivity and specificity than current biomarkers for malignant germ cell tumors (MGCT). Here, the performance of two methods commonly used to measure miR-371a-3p levels was compared: re…

Multiplex extended respiratory panels capable of detecting and differentiating viral and bacterial causes of respiratory tract infections have advanced substantially, however, their clinical utility remains inconclusive (1). Due to ongoing cost and rei…

Lung allografts are susceptible to myriad injury types, including acute rejection (AR), infectious disease (ID), baseline lung allograft dysfunction (BLAD), and chronic lung allograft dysfunction (CLAD), that impact outcomes. Donor-derived cell-free DN…