Autor: Aanum, A., Pereira, A., Andrew, B., Ramsden, C., Sollars, E., Shaw, J. M., Morgan, R. D., Burghel, G. J.
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Somatic panel testing reveals no common alternative oncogenic driver in BRCA1/2-mutant high-grade serous ovarian cancer with discordant low genomic instability score
IntroductionHigh-grade serous ovarian cancer (HGSOC) is the commonest and most lethal subtype of ovarian cancer, accounting for approximately 70% of cases and associated with a poor 10-year survival of 30%–40%.1 Around 40% of all HGSOCs exhibit h…
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Somatic panel testing reveals no common alternative oncogenic driver in BRCA1/2-mutant high-grade serous ovarian cancer with discordant low genomic instability score
IntroductionHigh-grade serous ovarian cancer (HGSOC) is the commonest and most lethal subtype of ovarian cancer, accounting for approximately 70% of cases and associated with a poor 10-year survival of 30%–40%.1 Around 40% of all HGSOCs exhibit h…