Autor: Alber Aqil, Betty Y.H. Huang, Pavlos Pavlidis, Rajiv C. McCoy, Omer Gokcumen
-
Mismapping of sequencing reads from polymorphic duplications generates spurious trans-eQTLs
Polymorphic gene duplications absent from the reference genome can generate spurious trans-eQTLs. Specifically, variants tagging the polymorphic duplicate may masquerade as trans-eQTLs regulating the reference gene copy. Here, we develop a method to id…
-
Mismapping of sequencing reads from polymorphic duplications generates spurious trans-eQTLs
Polymorphic gene duplications absent from the reference genome can generate spurious trans-eQTLs. Specifically, variants tagging the polymorphic duplicate may masquerade as trans-eQTLs regulating the reference gene copy. Here, we develop a method to id…