Autor: An Duong
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A 3′UTR polymorphism disrupts IRF2BP2 autoregulation through an eIF4H translational enhancer
IntroductionInterferon regulatory factor 2 binding protein 2 (IRF2BP2) suppresses the interferon response and inflammation. Individuals who carry 2 copies of a genetic variant (rs3045215) that deletes 9 nucleotides from the long 3′UTR of IRF2BP2 have l…