Autor: Daniel Munro, Alexander Gusev, Abraham A. Palmer, Pejman Mohammadi
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Data-driven RNA phenotyping captures genetically regulated dimensions of the transcriptome
Genetic variants can regulate many aspects of transcription, any of which could influence complex traits. We developed LaDDR, a method for generating latent data-driven RNA phenotypes from RNA sequencing read coverage. LaDDR substantially increases dis…
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Data-driven RNA phenotyping captures genetically regulated dimensions of the transcriptome
Genetic variants can regulate many aspects of transcription, any of which could influence complex traits. We developed LaDDR, a method for generating latent data-driven RNA phenotypes from RNA sequencing read coverage. LaDDR substantially increases dis…