Autor: Gao, M., Ren, J., Peng, C., Liu, X., Zheng, J., Chen, H., Chen, X., Wang, J., Lai, Y., Hu, T., Liu, S.
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Evaluating the efficiency of nanopore adaptive sampling sequencing in detecting balanced translocation
Background Balanced translocation (BT) carriers have a high risk of recurrent miscarriage and abnormal offspring due to unbalanced gamete production. Clinical genetic testing often fails to detect BTs that fall below microscopic resolution or occur in…
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Evaluating the efficiency of nanopore adaptive sampling sequencing in detecting balanced translocation
Background Balanced translocation (BT) carriers have a high risk of recurrent miscarriage and abnormal offspring due to unbalanced gamete production. Clinical genetic testing often fails to detect BTs that fall below microscopic resolution or occur in…