Autor: Jinghui Li, Xuanyao Liu
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Robust cis-by-trans epistasis in the human plasma proteome highlights an ABO-centered interaction network
Li et al. identify robust cis-by-trans epistatic interactions in the human plasma proteome. They uncover an ABO-centered epistatic regulatory network where blood type modifies cis-genetic effects on proteins, revealing a buffering mechanism consistent …
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Robust cis-by-trans epistasis in the human plasma proteome highlights an ABO-centered interaction network
Li et al. identify robust cis-by-trans epistatic interactions in the human plasma proteome. They uncover an ABO-centered epistatic regulatory network where blood type modifies cis-genetic effects on proteins, revealing a buffering mechanism consistent …