Autor: Luke J. O’Connor, Guy Sella
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Principled measures and estimates of trait polygenicity
The “polygenicity” of traits is often invoked, sometimes quantified, but rarely defined from first principles. Here, we define polygenicity measures and argue why the definition is sensible. We estimate three measures for 36 human traits and find that …
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Principled measures and estimates of trait polygenicity
The “polygenicity” of traits is often invoked, sometimes quantified, but rarely defined from first principles. Here, we define polygenicity measures and argue why the definition is sensible. We estimate three measures for 36 human traits and find that …