Autor: McVeigh, T. P., Hanson, H., Snape, K., Turnbull, C., Burghel, G. J.
-
Refinement of the UKCGG/CanVIG framework for triage of putative germline variants identified via tumour and ctDNA sequencing: maximising clinical utility and harmonising gene and variant-restricted reporting across UK clinical practice
WHAT IS ALREADY KNOWN ON THIS TOPICAnalysis of tumour (including circulating tumour) DNA may identify variants of possible germline origin, but determining which findings warrant germline follow-up is challenging.WHAT THIS STUDY ADDSWe present a framew…
-
Refinement of the UKCGG/CanVIG framework for triage of putative germline variants identified via tumour and ctDNA sequencing: maximising clinical utility and harmonising gene and variant-restricted reporting across UK clinical practice
WHAT IS ALREADY KNOWN ON THIS TOPICAnalysis of tumour (including circulating tumour) DNA may identify variants of possible germline origin, but determining which findings warrant germline follow-up is challenging.WHAT THIS STUDY ADDSWe present a framew…