Autor: Mihael Cudic, Justin D. Tubbs, Tian Ge, Jordan W. Smoller
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Putting polygenic scores in context: How intersectional factors affect relative and absolute genetic risk
Intersecting sociodemographic contexts meaningfully reshape genetic risk. Across 106 two-way intersections, polygenic scores showed substantial shifts in relative risk for seven diseases, whereas absolute risk changed more modestly after accounting for…
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Putting polygenic scores in context: How intersectional factors affect relative and absolute genetic risk
Intersecting sociodemographic contexts meaningfully reshape genetic risk. Across 106 two-way intersections, polygenic scores showed substantial shifts in relative risk for seven diseases, whereas absolute risk changed more modestly after accounting for…
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Putting polygenic scores in context: How intersectional factors affect relative and absolute genetic risk
Intersecting sociodemographic contexts meaningfully reshape genetic risk. Across 106 two-way intersections, polygenic scores showed substantial shifts in relative risk for seven diseases, whereas absolute risk changed more modestly after accounting for…