Autor: Shi, Z., Mulford, A. J., Wei, J., Tran, H., Ashworth, A., Zheng, S. L., Lu, J., Sanders, A. R., Helfand, B., Xu, J.

BackgroundCurrent clinical approaches to inherited prostate cancer (PCa) risk rely on binary classification of pathogenic variant (PV) carrier status without accounting for gene-specific heterogeneity or polygenic risk. We developed an integrated genet…

BackgroundCurrent clinical approaches to inherited prostate cancer (PCa) risk rely on binary classification of pathogenic variant (PV) carrier status without accounting for gene-specific heterogeneity or polygenic risk. We developed an integrated genet…