Autor: Winarni, T. I., Yrigollen, C. M., Durbin-Johnson, B., Schneider, A., Hagerman, R., Tassone, F.
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Maternal FMR1 premutation covariates correlate with intergenerational expansion and neuropsychiatric conditions
WHAT IS ALREADY KNOWN ON THIS TOPICThis study supports a multidimensional model of FMR1 premutation biology in which CGG repeat structure, maternal age and FMR1 mRNA levels contribute to the risk of multigenerational expansion.WHAT THIS STUDY ADDSIn ad…