Autor: Yijing Zhao, Dale Annear, Emily G. Allen, R. Frank Kooy, David L. Nelson, Peng Jin
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Polymorphic CGG repeats in gene regulation and disease
Polymorphic CGG repeats are emerging as dynamic regulators of gene expression and genome stability. This review highlights how their expansion drives diverse neurodevelopmental and neurodegenerative disorders through epigenetic silencing, RNA toxicity,…
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Polymorphic CGG repeats in gene regulation and disease
Polymorphic CGG repeats are emerging as dynamic regulators of gene expression and genome stability. This review highlights how their expansion drives diverse neurodevelopmental and neurodegenerative disorders through epigenetic silencing, RNA toxicity,…