Categoría: Articulos
-
Primate-specific DNA change reveals a new link to dementia-related neurodegeneration
Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional a…
-
Primate-specific DNA change reveals a new link to dementia-related neurodegeneration
Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional a…
-
Next-generation RNA approach provides hope for genetic diseases missed by current drugs
Researchers at the University of Toronto have developed a next-generation RNA therapeutic approach with the potential to treat a wide range of genetic diseases that share certain disease-causing mutations. The work advances an emerging platform in gene…
-
Next-generation RNA approach provides hope for genetic diseases missed by current drugs
Researchers at the University of Toronto have developed a next-generation RNA therapeutic approach with the potential to treat a wide range of genetic diseases that share certain disease-causing mutations. The work advances an emerging platform in gene…
-
Largest ever molecular map of autism opens new paths to precision therapies
For more than two decades, researchers have identified hundreds of genes that increase the risk of autism spectrum disorder (ASD). Yet multiple fundamental questions have remained unanswered: Among them, how do mutations in these genes lead directly to…
-
Largest ever molecular map of autism opens new paths to precision therapies
For more than two decades, researchers have identified hundreds of genes that increase the risk of autism spectrum disorder (ASD). Yet multiple fundamental questions have remained unanswered: Among them, how do mutations in these genes lead directly to…
-
Histone tail mutants: versatile tools for decoding chromatin, development, and disease
Histone modifications have been associated with transcriptional regulation, development, and disease, yet their direct functional roles remain incompletely understood due to the redundancy and promiscuity of cognate histone-modifying enzymes. Experimen…
-
Utility of Face2Gene’s DeepGestalt and D-Score applications in paediatric neurodevelopmental disorders in South Africa
European Journal of Human Genetics, Published online: 27 August 2026; doi:10.1038/s41431-026-02216-5Utility of Face2Gene’s DeepGestalt and D-Score applications in paediatric neurodevelopmental disorders in South Africa
-
More accurate risk assessment developed for Alzheimer’s disease among nonwhite patients
Late-onset Alzheimer’s disease (AD) is a progressive disorder characterized by cognitive decline and memory impairment, affecting an estimated 6.9 million people in the U.S. The clinical course of AD unfolds over many years, often beginning with subtle…