Categoría: Trends in Genetics
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From mobile DNA to medicine: Fusion Conference highlights the therapeutic potential of endogenous retroelements in human disease
Endogenous retroelements (EREs) are a subset of transposable elements (TEs) that mobilize via an RNA intermediate. They include retrotransposable elements such as long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs…
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From mobile DNA to medicine: Fusion Conference highlights the therapeutic potential of endogenous retroelements in human disease
Endogenous retroelements (EREs) are a subset of transposable elements (TEs) that mobilize via an RNA intermediate. They include retrotransposable elements such as long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs…
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Emergence of protein-coding enhancer RNAs in primate evolution
Enhancer RNAs (eRNAs) are short, unstable RNA polymerase II transcripts from active enhancers processed by the Integrator complex. Once considered noncoding, recent work from Vlasov et al. shows that a subset of eRNAs contain open reading frames transl…
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Emergence of protein-coding enhancer RNAs in primate evolution
Enhancer RNAs (eRNAs) are short, unstable RNA polymerase II transcripts from active enhancers processed by the Integrator complex. Once considered noncoding, recent work from Vlasov et al. shows that a subset of eRNAs contain open reading frames transl…